My conversation with Aubrey de Grey, a biomedical gerontologist, founder of the LEV Foundation, and author of Ending Aging.
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Timestamps
0:00 - SENS vs. the Hallmarks of Aging
2:47 - The Robust Mouse Rejuvenation experiment
5:48 - Is SENS falsifiable?
7:12 - CMLase and extracellular matrix damage
10:28 - VEGF and extending lifespan in mice
11:37 - Why longevity studies rarely get replicated
13:05 - Michael Levin, bioelectricity & aging as information loss
15:03 - Is partial reprogramming overhyped?
17:32 - The most neglected areas of longevity research
18:56 - Longevity escape velocity explained
20:28 - Will people alive today live long enough?
23:42 - How far are we from dramatically extending mouse lifespan?
24:54 - What happens to society if we solve aging?
27:20 - How longevity could reshape the global economy
28:44 - Does mortality give life meaning?
30:00 - Aubrey on the “pro-aging trance”
31:34 - What Aubrey would do after solving aging
